解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Caesalpinone A (1), a new type of gorgonane sesquiterpenoid containing an unprecedented 1,15-bridge, along with ten known sesquiterpenoids (2-11) were isolated from the pods of Caesalpinia spinosa Kuntze (Tara). The structure of caesalpinone A was elucidated based on its 1D and 2D NMR spectra. The absolute configurati...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.06.012
更新日期:2016-07-01 00:00:00
abstract::The last few decades have seen an alarming rise in fungal infections, which currently represent a global health threat. Despite extensive research towards the development of new antifungal agents, only a limited number of antifungal drugs are available in the market. The routinely used polyene agents and many azole an...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2016.05.016
更新日期:2016-07-01 00:00:00
abstract::Acteoside, which belongs to the family of phenylethanoid glycosides (PhGs), has extensive biological activities, including strong antioxidant, anti-inflammatory, hepatoprotect, and cell apoptosis regulation. Like other PhGs compounds, the fate of acteoside in the gut for both parent polyphenols and their degradation p...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.05.004
更新日期:2016-07-01 00:00:00
abstract::Crude CH2Cl2 extract from leaves of Piper laevicarpu (Piperaceae) displayed antitrypanosomal activity against trypomastigote forms of Trypanosoma cruzi (Y strain) and antimicrobial potential against Cryptococcus gattii (strain-type WM 178). Bioactivity-guided fractionation of crude extract afforded one new natural bio...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.04.005
更新日期:2016-06-01 00:00:00
abstract::Five new carboxymethyl flavonoids named 5-carboxymethyl-3', 4', 7-trihydroxyflavone (1), (2S)- 5-carboxymethyl-3', 4', 7-trihydroxyflavonone (2a), (2R)-5-carboxymethyl-3', 4', 7-trihydroxyflavonone (2b), (2S)-5-carboxymethyl-4', 7-dihydroxyflavonone (3), 5- carbomethoxymethyl-4', 7-dihydroxyflavone (4), and a new chro...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.04.022
更新日期:2016-06-01 00:00:00
abstract::Two new depsidones, schomburgdepsidones A and B (1 and 2), and one new xanthone, schomburgxanthone A (3), together with eight known compounds (4-11) were isolated from the roots of Garcinia schomburgkiana. Their chemical structures were established on the basis of spectroscopic analysis. The in vitro cytotoxicity of a...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.04.012
更新日期:2016-06-01 00:00:00
abstract::The purpose of this study was to evaluate the tyrosinase inhibitory capacity of Populus nigra buds absolute (PBA) and compare it to kojic acid (KA), controversial reference tyrosinase inhibitor. Populus nigra buds were extracted with hexane and ethanol to obtain PBA. The inhibitory effect of this absolute was first te...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.04.001
更新日期:2016-06-01 00:00:00
abstract::Five new sesquiterpenoids, including two linderanes (1-2) and three eudesmanes (3-5) were isolated from the seeds of Sarcandra glabra. Their structures and relative configurations were established by spectroscopic data analysis. 1 was a rare linderane derivative having an 18-membered triester ring which is a common ch...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.03.020
更新日期:2016-06-01 00:00:00
abstract::Chemical investigation of the liquid culture of the endophytic fungus Bipolaris sorokiniana A606, which was isolated from the medicinal plant Pogostemon cablin resulted in the isolation of four new cytotoxic compounds, named isocochlioquinones D-E (1-2) and cochlioquinones G-H (3-4), along with five known cochlioquino...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.02.005
更新日期:2016-04-01 00:00:00
abstract::Three new clerodane type diterpenoids (2-4), together with one known analogues (1), were isolated from the tuberous roots of Tinospora sagittata (Oliv.) Gagnep. Compound 3 is an unusual clerodane diterpenoid with the carbonyl functionality at C-3, which represents the first example from this diterpenoid compounds clas...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.02.012
更新日期:2016-04-01 00:00:00
abstract::Herbal medicines are the most globally used type of medical drugs. Their high cultural acceptability is due to the experienced safety and efficiency over centuries of use. Many of them are still phytochemically less-investigated, and are used without standardization or quality control. Choosing SIROP KILMA, an authori...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.03.012
更新日期:2016-04-01 00:00:00
abstract::Diketopiperazine is a natural products found from bacteria, fungi, marine sponges, gorgonian and red algae. They are cyclic dipeptides possessing relatively simple and rigid structures with chiral nature and various side chains. The compounds in this structure class have been known to possess diverse bioactivities inc...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.03.016
更新日期:2016-04-01 00:00:00
abstract::Seven new 2-(2-phenylethyl)chromone derivatives (1-7) including a chlorinated one (4), together with eight known ones (8-15), were isolated from the EtOAc extract of artificial agarwood originating from Aquilaria sinensis (Lour.) Gilg. All structures including the absolute configurations were unambiguously elucidated ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.01.011
更新日期:2016-04-01 00:00:00
abstract::The first chemical examination of roots of the traditionally used medicinal plant Talinum triangulare (Portulacaceae) from Nigeria led to the isolation of two new C-methylated flavonoids, 5,6-dimethoxy-7-hydroxy-8-methyl-flavone (1), 5,6-dimethoxy-8-methyl-2-phenyl-7H-1-benzopyran-7-one (2), and one new α-pyrone deriv...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.01.002
更新日期:2016-03-01 00:00:00
abstract::Australian native plants have a long history of therapeutic use in indigenous cultures, however, they have been poorly studied scientifically. We analysed the effects of 14 plant derived compounds from the species Pilidiostigma glabrum, Myoporum montanum, Geijera parviflora, and Rhodomyrtus psidioides for their potent...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.12.010
更新日期:2016-03-01 00:00:00
abstract::Three new phloroglucinols, baeckenones D-F (1-3), were obtained from the leaves of Indonesian Baeckea frutescens, along with the known unusual endoperoxide, phloroglucinol (4). The structures of the isolated compounds were elucidated by 1D and 2D NMR and HREIMS spectra. Furthermore, the stereochemistry of baeckenone D...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2016.01.013
更新日期:2016-03-01 00:00:00
abstract::Curcuminoids possess powerful antioxidant activity as demonstrated in many chemical in vitro tests and in several in vivo trials. Nevertheless, the mechanism of this activity is not completely elucidated and studies on the in vivo antioxidant effects are still needed. Metabolomics may be used as an attractive approach...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.12.013
更新日期:2016-03-01 00:00:00
abstract::Cyclotides describe a unique cyclic peptide family that displays a broad range of biological activities including uterotonic, anti-bacteria, anti-cancer and anti-HIV. The vigno cyclotides consist of vigno 1-10 were reported recently from Viola ignobilis. In the present study, we examined the effects of vigno 5, a natu...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.12.021
更新日期:2016-03-01 00:00:00
abstract::Beyond its role in the activation of protein C, the endothelial cell protein C receptor (EPCR) plays an important role in the cytoprotective pathway. EPCR can be shed from the cell surface, which is mediated by tumor necrosis factor-α converting enzyme (TACE). Polyozellin, a major constituent of a Korea edible mushroo...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.11.005
更新日期:2016-01-01 00:00:00
abstract::Chemical examination of the ethanol extract of rhizomes of Iris tectorum led to the isolation and characterization of three new lignans, (7R,7'R,8S,8'S)-5'-methoxy-neo-olivil (1a), (7S,7'S,8R,8'R) -5'-methoxy-neo-olivil (1b), (7S,7'R,8S,8'S)-neo-olivil (2a), (7R,7'S,8R,8'R)-neo-olivil (2b), (7R,7'R,8S,8'S,7''S,8''S)-t...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.11.020
更新日期:2016-01-01 00:00:00
abstract::Three new xanthones, cylindroxanthones A-C (1-3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluat...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.11.017
更新日期:2016-01-01 00:00:00
abstract::Two new triterpenoid estersaponins (1, 2) were isolated from the leaves of Pittosporum tobira 'Variegata' (Thunb.) W. T. Aiton, along with one known saponin (3) and one known flavonoid glycoside (4). Their structures were established by different spectroscopic methods including 1D and 2D NMR, UV, as well as ESI-MS ana...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.09.006
更新日期:2015-10-01 00:00:00
abstract::Two pairs of enantiomers of flavonoid oligomers (1a and 1b, 2a and 2b) along with one known chalcone (3) were isolated from the rhizomes of Alpinia platychilus. Their structures were elucidated on the basis of spectroscopic data (MS and 1D/2D NMR). The absolute configurations of the flavonoid oligomers were establishe...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.09.010
更新日期:2015-10-01 00:00:00
abstract::In our ongoing efforts of finding natural fungicides to fight food and feed spoilage during production and storage, the antifungal potential of Ghanaian Uvaria chamae P. Beauv. was investigated, with emphasis on plant metabolites targeting the fungal plasma membrane (PM) H(+)-ATPase. Ethyl acetate extract of U. chamae...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.06.013
更新日期:2015-09-01 00:00:00
abstract::Three new steroidal glycosides (1-3) and a novel natural product 4 firstly obtained from a plant source, together with two known steroidal glycosides (5-6) have been isolated from the whole plant of Reineckia carnea. Their structures were determined by physicochemical properties and spectroscopic methods, and their cy...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.07.008
更新日期:2015-09-01 00:00:00
abstract::A new altersolanol derivative, 4-dehydroxyaltersolanol A (9), along with two known sesquiterpenoids, (S)-7'-hydroxyabscisic acid (7) and (S)-abscisic acid (8) were obtained from the endophytic fungus, Nigrospora oryzae, isolated from leaves of Combretum dolichopetalum. The host plant yielded six known compounds includ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.06.018
更新日期:2015-09-01 00:00:00
abstract::A new phenylpropanoid glucoside and two new neolignans, namely (1S, 2R)-1-(3, 4, 5-trimethoxyphenyl)-3-(β-d-glucopyranosyloxy)-1, 2, 3-propanetriol (1), and (7R, 8R)-4, 7, 9, 9'-tetrahydroxy-3, 5, 3', 5'-tetramethoxy-8-4'-oxyneolignan 4-O-β-d-glucopyranoside (2) and 3', 9, 9'-trihydroxy-3, 5-dimethoxy-8-O-4'-neolignan...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.05.010
更新日期:2015-07-01 00:00:00
abstract::Phytochemical study on rhizomes of Beesia calthifolia resulted in the isolation of five new (1-5) and three known (6-8) cycloartane triterpenoids possessing a hemiketal or ketal group at C-24 from the EtOAc fraction of 95% ethanol extract. Their structures were determined by spectroscopic and chemical methods, especia...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.04.017
更新日期:2015-06-01 00:00:00
abstract::Five new benzylphenanthrenes, cremaphenanthrenes L-P (1-5) were isolated from the EtOAc-soluble extract of the tubers of Cremastra appendiculata. Their structures were elucidated based on the spectroscopic data and chemical methods. Compounds 1-5 were tested in vitro for their cytotoxic effects against colon (HCT-116)...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.03.003
更新日期:2015-06-01 00:00:00
abstract::In the last 20 years, wine phenolic compounds have received increasing interest since several epidemiological studies have suggested associations between regular consumption of moderate amount of wine and prevention of certain chronic pathologies, such as neurodegenerative diseases. This study was aimed to investigate...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.04.003
更新日期:2015-06-01 00:00:00
abstract::A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of t...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.03.022
更新日期:2015-06-01 00:00:00
abstract:AIM:The current study was designed to explore the mechanism of the prokinetic activity of Gentiopicroside (Ge), from Gentiana macrophylla Pall which is widely used to strengthen gastric motility in clinic. METHODS:Gastrointestinal motility disorder rats were induced by stress stimulation and the rats were treated with...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.04.015
更新日期:2015-06-01 00:00:00
abstract::Three new xanthones, named kaennacowanols A-C (1-3), along with nineteen known xanthones were isolated from the roots of Garcinia cowa Roxb. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cell lines. Compounds 17 and 22 showe...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.03.008
更新日期:2015-04-01 00:00:00
abstract::Three new secoiridoid aglycones of (-)-swermusic acid A (1) and B (3), and (-)-swerimuslatone A (2), and four new secoiridoid glycosides of 6'-O-formylsweroside (4), 6'-O-formylgentiopicroside (5), 6'-O-acetylamarogentin (6) and 6'-O-acetylamaronitidin (7), along with 40 known compounds (8-47) were isolated from Swert...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.01.020
更新日期:2015-04-01 00:00:00
abstract::The fruit rind of Garcinia gummi-gutta, commonly known as Garcinia cambogia (syn.), is extensively used traditionally as a flavourant in fish curries due to its sharp sour taste. Additional ethnobotanical uses include its use as a digestive and a traditional remedy to treat bowel complaints, intestinal parasites and r...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2015.02.012
更新日期:2015-04-01 00:00:00
abstract::Investigation of the bioactive secondary metabolites of the marine actinomycetes Rubrobacter radiotolerans led to the isolation and characterization of two naturally rare dimeric indole derivatives (1 and 2). The structures of these new compounds were elucidated by spectroscopic data interpretation, and the absolute c...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.01.014
更新日期:2015-04-01 00:00:00
abstract::Diplacone (1) and mimulone (2), two geranylated flavanones, have previously shown anti-inflammatory and antiradical activity in vitro. The present study aimed to evaluate their activity in vivo on a model of colitis induced in Wistar rats by an oral administration of dextran sulfate sodium (DSS). Diplacone (1) and mim...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2015.01.012
更新日期:2015-03-01 00:00:00
abstract::One new phenanthrene, aphyllone A (1) and four new bibenzyl derivatives, aphyllone B (2) and aphyllals C-D (3-5), together with nine known compounds (6-14), were isolated from the stems of Dendrobium aphyllum (Roxb.) C. E. Fischer. The structures of these new compounds were elucidated by means of extensive spectroscop...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.11.004
更新日期:2015-01-01 00:00:00
abstract::Two novel 2-arylbenzofuran dimers, shandougenines A (1) and B (2), and two new polyisoprenylated flavanones 3 (shandougenine C) and 4 (shandougenine D) were isolated from the 95% EtOH extract of Sophora tonkinensis, together with 18 known compounds. Their structures were determined on the basis of spectral data interp...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.08.019
更新日期:2014-12-01 00:00:00
abstract::Hepatitis C virus (HCV) infection is highly prevalent among global populations, with an estimated number of infected patients being 170 million. Approximately 70-80% of patients acutely infected with HCV will progress to chronic liver disease, such as liver cirrhosis and hepatocellular carcinoma, which is a substantia...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2014.10.011
更新日期:2014-12-01 00:00:00